Anette Roop (Hugo Treffneri Gümnaasium) recently conducted her student research project within our group, focusing on novel models of early embryo implantation and the characterization of human chorionic gonadotropin (hCG) activity in these systems.Her project, titled “Measurement of the Biological Activity of Human Chorionic Gonadotropin in Samples Derived from an Embryo Implantation Model System”, was […]

Anni’s research focuses on G protein–coupled receptors (GPCRs), a major class of membrane proteins that mediate neuronal signaling and are implicated in numerous diseases. Approximately one third of FDA‑approved drugs target GPCRs, highlighting their clinical importance. Her research group in personalized pharmacology investigates how genetic variation in GPCRs affects drug efficacy, with the aim of […]

Understanding how ligands engage the muscarinic M1 receptor is key to advancing therapies for neurodegenerative disorders. In this study, we introduce complementary kinetic fluorescence approaches that enable real‑time monitoring of ligand binding at the M1 receptor with high sensitivity. Using the fluorescent tracer UR‑MK342, we not only obtain robust affinity estimates across a diverse panel […]